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Publikationen

  • Thomas J. Schmidt, Shiva Hemmati, Michael Klaes, Belma Konuklugil, Abdolali Mohagheghzadeh, Iliana Ionkova, Elisabeth Fuss, A. Wilhelm Alfermann; Lignans in flowering aerial parts of Linum species - Chemodiversity in the light of systematics and phylogen; Phytochemistry (2010), doi: 10.1016/j.phytochem.2010.06.015
  • Hemmati, Shiva; Heimendahl, Cosima B. I. von; Klaes, Michael; Alfermann, A. Wilhelm; Schmidt, Thomas J.; Fuss, Elisabeth: Pinoresinol-Lariciresinol Reductases with Opposite Enantiospecificity Determine the Enantiomeric Composition of Lignans in the Different Organs of Linum usitatissimum L. Planta Med 2010; 76: 928-934
  • A.W. Alfermann Production of natural products by plant cell and organ cultures In: M. Wink, ed. (2009), Annual Plant Reviews vol. 39: Functions and Biotechnology of Plant Secondary Metabolites, pp. 381 - 397
  • High-performance liquid chromatography/mass spectrometric identification of dibenzylbutyrolactone-type lignans: insights into electrospray ionization tandem mass spectrometric fragmentation of lign-7-eno-9,9'-lactones and application to the lignans of Linum usitatissimum L. (Common Flax). Schmidt, Thomas J.; Alfermann, A. Wilhelm; Fuss, Elisabeth. Rapid Communications in Mass Spectrometry (2008), 22(22), 3642-3650
  • Hinokinin biosynthesis in Linum corymbulosum Reichenb. Bayindir, Ueruen; Alfermann, August Wilhelm; Fuss, Elisabeth. Plant Journal (2008), 55(5), 810-820
  • Metabolic profiling of lignan variability in Linum species of section syllinum native to Bulgaria. Vasilev, Nikolay; Ebel, Rainer; Edrada, RuAngelie; Fuss, Elisabeth; Alfermann, A. Wilhelm; Ionkova, Iliana; Petrova, Ana; Repplinger, Miriam; Schmidt, Thomas J. Planta Medica (2008), 74(3), 273-280.
  • Stereochemistry of lignans in Phaleria macrocarpa (Scheff.) Boerl. Saufi, Ahmad; von Heimendahl, Cosima B. I.; Alfermann, A. Wilhelm; Fuss, Elisabeth. Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2008), 63(1/2), 13-16
  • Justicidin B 7-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum perenne Himmelszelt involved in the biosynthesis of diphyllin. Hemmati, Shiva; Schneider, Bernd; Schmidt, Thomas J.; Federolf, Katja; Alfermann, A. Wilhelm; Fuss, Elisabeth. Phytochemistry (2007), 68(22-24), 2736-2743
  • Aryltetralin-lignan formation in two different cell suspension cultures of Linum album: Deoxypodophyllotoxin 6-hydroxylase, a key enzyme for the formation of 6-methoxypodophyllotoxin. Federolf, Katja; Alfermann, A. Wilhelm; Fuss, Elisabeth. Phytochemistry (2007), 68(10), 1397-1406
  • Lignans from Linum species of sections Syllinum and Linum. Konuklugil, B.; Ionkova, I.; Vasilev, N.; Schmidt, T. J.; Windhovel, J.; Fuss, E.; Alfermann, A. W.. Natural Product Research, Part A: Structure and Synthesis (2007), 21(1), 1-6. (+)-Pinoresinol/(-)-lariciresinol reductase from Linum perenne Himmelszelt involved in the biosynthesis of justicidin B. Hemmati, Shiva; Schmidt, Thomas J.; Fuss, Elisabeth. FEBS Letters (2007), 581(4), 603-610.
  • Diarylbutyrolactone lignans from Linum corymbulosum in vitro cultures. Mohagheghzadeh, Abdolali; Schmidt, Thomas J.; Bayindir, Urun; Fuss, Elisabeth; Mehregan, Iraj; Alfermann, A. Wilhelm. Planta Medica (2006), 72(12), 1165-1167
  • A combined HPLC-UV and HPLC-MS method for the identification of lignans and its application to the lignans of Linum usitatissimum L. and L. bienne Mill. Schmidt, Thomas J.; Hemmati, Shiva; Fuss, Elisabeth; Alfermann, A. Wilhelm. Phytochemical Analysis (2006), 17(5), 299-311
  • Sustainable bioproduction of phytochemicals by plant in vitro cultures: anticancer agents. Wink, Michael; Alfermann, A. Wilhelm; Franke, Rochus; Wetterauer, Bernhard; Distl, Melanie; Windhoevel, Joerg; Krohn, Oliver; Fuss, Elisabeth; Garden, Hermann; Mohagheghzadeh, Abdolali; Wildi, Eckart; Ripplinger, Peter. Plant Genetic Resources (2005), 3(2), 90-100
  • Linum mucronatum: Organ to organ lignan variations. Mohagheghzadeh, Abdolali; Gholami, Azra; Soltani, Mohammad; Hemmati, Shiva; Alfermann, A. Wilhelm. Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2005), 60(5/6), 508-510
  • Influence of methyl jasmonate on podophyllotoxin and 6-methoxypodophyllotoxin accumulation in Linum album cell suspension cultures. Fuerden, Betina; Humburg, Anne; Fuss, Elisabeth. Plant Cell Reports (2005), 24(5), 312-317
  • Linum persicum: lignans and placement in Linaceae. Mohagheghzadeh, Abdolali; Hemmati, Shiva; Mehregan, Iraj; Alfermann, A. Wilhelm. Phytochemistry Reviews (2004), Volume Date 2003, 2(3), 363-369
  • Lignans in plant cell and organ cultures: An overview. Fuss, Elisabeth. Phytochemistry Reviews (2004), Volume Date 2003, 2(3), 307-320.
  • Comparison of different extraction methods for the determination of podophyllotoxin and 6-methoxypodophyllotoxin in Linum species. Kartal, Murat; Konuklugil, Belma; Indrayanto, Gunawan; Alfermann, A. W.. Journal of Pharmaceutical and Biomedical Analysis (2004), 35(3), 441-447.
  • Glucosylation of p-tyrosol to salidroside by Rhodiola rosea L. cell cultures. Furmanowa, M.; Hartwich, M.; Alfermann, A. W.. Herba Polonica (2002), 48(2), 71-76
  • Biosynthesis of podophyllotoxin in Linum album cell cultures. Seidel, Veronique; Windhovel, Jorg; Eaton, Graham; Alfermann, A. Wilhelm; Arroo, Randolph R. J.; Medarde, Manuel; Petersen, Maike; Woolley, Jack G. Planta (2002), 215(6), 1031-1039.
  • Aspects of cytotoxic lignan biosynthesis in suspension cultures of Linum nodiflorum. Kuhlmann, S.; Kranz, K.; Lucking, B.; Alfermann, A. W.; Petersen, M. Phytochemistry Reviews (2002), 1(1), 37-43
  • Plant cell factories as a source for anti-cancer lignans. Arroo, R. R. J.; Alfermann, A. W.; Medarde, M.; Petersen, M.; Pras, N.; Woolley, J. G. Phytochemistry Reviews (2002), 1(1), 27-35.
  • Production of paclitaxel and baccatin III in a 20-L airlift bioreactor by a cell suspension of Taxus wallichiana. Navia-Osorio, A.; Garden, H.; Cusido, R. M.; Palazon, J.; Alfermann, A. W.; Pinol, M. T. Planta Medica (2002), 68(4), 336-340
  • Taxol and baccatin III production in suspension cultures of Taxus baccata and Taxus wallichiana in an airlift bioreactor. Navia-Osorio, Alberto; Garden, Hermann; Cusido, Rosa M.; Palazon, Javier; Alfermann, A. Wilhelm; Pinol, M. Teresa. Journal of Plant Physiology (2002), 159(1), 97-102
  • Accumulation of lignans in suspension cultures of Linum mucronatum ssp. armenum (Bordz.) Davis. Konuklugil, Belma; Schmidt, Thomas J.; Alfermann, A. Wilhelm. Zeitschrift fuer Naturforschung, C: Journal of Biosciences (2001), 56(11/12), 1164-1165
  • Arylnaphthalene lignans from in vitro cultures of Linum austriacum. Mohagheghzadeh, Abdolali; Schmidt, Thomas J.; Alfermann, A. Wilhelm. Journal of Natural Products (2002), 65(1), 69-71.
  • Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans. Molog, Grietje Antje; Empt, Ursula; Kuhlmann, Stephan; van Uden, Wim; Pras, Niesko; Alfermann, August Wilhelm; Petersen, Maike. Planta (2001), 214(2), 288-294
  • Induction of tropane alkaloid formation as a result of a heavy metal toxicity: dose-response relation in suspension and transformed root cultures of Datura stramonium L. treated with cadmium. Ionkova, I.; Demeyer, K.; Tsvetanova, V.; Ninov, S.; Alfermann, A. W.. Farmatsiya (Sofia) (1999), 46(4), 14-17
  • The production of cytotoxic lignans by plant cell cultures. Petersen, Maike; Alfermann, A. Wilhelm. Applied Microbiology and Biotechnology (2001), 55(2), 135-142 Metabolic engineering of plant secondary metabolism. Verpoorte, R.; Alfermann, A. W.; Editors. Neth. (2000), 286 pp. Publisher: (Kluwer, Dordrecht, Neth.)
  • The use of plant cell cultures for the production of podophyllotoxin and related lignans. Empt, Ursula; Alfermann, A. Wilhelm; Pras, Niesko; Petersen, Maike. Journal of Applied Botany (2000), 74(3/4), 145-150
  • Rosavin as a product of glycosylation by Rhodiola rosea (roseroot) cell cultures. Furmanowa, Miroslawa; Hartwich, Malgorzata; Alfermann, August W.; Kozminski, Wiktor; Olejnik, Marian. Plant Cell, Tissue and Organ Culture (1999), 56(2), 105-110.
  • Production of secondary metabolites in cell and differentiated organ cultures. Walton, N. J.; Alfermann, A. W.; Rhodes, M. J. C. Annual Plant Reviews (1999), 3(Functions of Plant Secondary Metabolites and Their Exploitation in Biotechnology), 311-345. Publisher: Sheffield Academic Press, ISSN: 1460-1494
  • Genetic transformation of Salvia miltiorrhiza. Hu, Z. B.; Liu, D.; Alfermann, A. W.. Biotechnology in Agriculture and Forestry (1999), 45 (Transgenic Medicinal Plants), 249-260. Publisher: Springer-Verlag, ISSN: 0934-943X
  • Accumulation of aryltetralin lactone lignans in cell suspension cultures of Linum nodiflorum. Konuklugil, B.; Schmidt, T. J.; Alfermann, A. Wilhelm. Planta Medica (1999), 65(6), 587-588
  • Accumulation of podophyllotoxin and related lignans in cell suspension cultures of Linum album. Smollny, Thomas; Wichers, Harry; Kalenberg, Sabine; Shahsavari, Abbas; Petersen, Maike; Alfermann, A. Wilhelm. Phytochemistry (1998), 48(6), 975-979
  • High forskolin production in hairy roots of Coleus forskohlii. Sasaki, K.; Udagawa, A.; Ishimaru, H.; Hayashi, T.; Alfermann, A. W.; Nakanishi, F.; Shimomura, K. Plant Cell Reports (1998), 17(6-7), 457-459
  • Sesquiterpene lactone content in leaves of in vitro and field cultivated Arnica montana. Schmidt, Thomas J.; Bomme, U.; Alfermann, A. W.. Planta Medica (1998), 64(3), 268-270
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