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Publications

  • Rastogi, S.K., van Wijlick, L., Ror, S., Lee, K.K., Román, E., Agarwal, P., Manzoor, N., Gow, N.A.R., Pla, J., Ernst, J.F., Panwar, S.L. (2019) Ifu5, a WW domain-containing protein interacts with Efg1 to achieve coordination of normoxic and hypoxic functions to influence pathogenicity traits in Candida albicans. Cell. Microbiol. Nov 17:e13140.
  • Desai, P.R., Lengeler, K., Kapitan, M., Janßen, S.M., Alepuz, P., Jacobsen, I.D., Ernst, J.F. (2018) The 5' untranslated region of the EFG1 transcript promotes its translation to regulate hyphal morphogenesis in Candida albicansmSphere 3: e00280-18. (Selected article by "Faculty of 1000")

  • Pohlers, S., Martin, R., Krüger, T., Hellwig, D., Hänel, F., Kniemeyer, O., Saluz, H.P., Van Dijck, P., Ernst, J.F., Brakhage, A., Mühlschlegel, F.A., Kurzai, O. (2017) Lipid signaling via Pkh1/2 regulates fungal CO2 sensing through the kinase Sch9. MBio 8: pii: e02211-16.

  • van Wijlick, L., Geissen, R., Hilbig, J.S., Lagadec, Q., Cantero, P.D., Pfeifer, E., Juchimiuk, M.,  Kluge, S., Wickert, S., Alepuz, P., Ernst, J.F. (2016) Dom34 links translation to protein O-mannosylation. PLoS Genet. 12: e1006395. DMYKG publication award  
  • van Wijlick, L., Swidergall, M., Brandt, P., Ernst, J.F. (2016) Candida albicans responds to glycostructure damage by Ace2-mediated feedback regulation of Cek1 signaling. Mol. Microbiol. 102: 827-849.
  • Buerth, C., Tielker, D., Ernst, J.F. (2016) Candida utilis and Cyberlindnera (Pichia) jadinii: yeast relatives with expanding applications. Appl. Microbiol. Biotechnol. 100: 6981-6990.
  • Kapitan, M., Eichhof, I., Lagadec, Q., Ernst, J.F. (2016) Click beetle luciferases as dual reporters of gene expression in Candida albicans. Microbiology, 162: 1310-1320.
  • Buerth, C., Mausberg, A.K., Heininger, M.K., Hartung, H.P., Kieseier, B.C., Ernst, J.F. (2016) Oral tolerance induction in experimental autoimmune encephalomyelitis with Candida utilis expressing the immunogenic MOG35-55 Peptide. PLoS One 11: e0155082.
  • Eichhof, I., Ernst, J.F. (2016) Oxygen-independent FbFP: Fluorescent sentinel and oxygen sensor component in Saccharomyces cerevisiae and Candida albicansFungal Genet. Biol. 92: 14-25. Corrigendum 93: 62.
  • Desai, P., van Wijlick, L., Kurtz, D., Juchimiuk, M., Ernst, J.F. (2015) Hypoxia and temperature regulated morphogenesis in Candida albicansPLoS Genet. 11: e1005447.
  • Rupp, O., Brinkrolf. K., Buerth, C., Kunigo, M., Schneider, J., Jaenicke, S., Goesmann, A., Pühler, A., Jaeger, K.E., Ernst, J.F. (2015) The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. J. Biotechnol. 211: 20-30.
  • Kunigo, M., Buerth, C., Ernst, J.F. (2015) Secreted xylanase XynA mediates utilization of xylan as sole carbon source in Candida utilisAppl. Microbiol. Biotechnol. 99: 8055-8064.
  • Swidergall, M., van Wijlick, L., Ernst, J.F. (2015) Signaling domains of mucin Msb2 in Candida albicans. Eukaryot. Cell 14: 359-370.
  • Varshney, N., Schaekel, A., Singha, R., Chakraborty, T., van Wijlick, L., Ernst, J. F., Sanyal, K. (2015) A surprising role for the Sch9 protein kinase in chromosome segregation in Candida albicans. Genetics 199: 671-674. (Comment in SGD News & Newsworthy)
  • Swidergall, M., Ernst, J. F. (2014) Interplay between Candida albicans and the antimicrobial peptide armory. Eukaryot. Cell 13: 950-957.
  • Juchimiuk, M., Orłowski, J., Gawarecka, K., Swieżewska, E., Ernst, J. F., Palamarczyk, G. (2014) Candida albicans cis-prenyltransferase Rer2 is required for protein glycosylation, cell wall integrity and hypha formation. Fungal Genet. Biol. 69C:1-12.
  • Schaekel, A., Desai, P. R., Ernst, J. F. (2013) Morphogenesis-regulated localization of protein kinase A to genomic sites in Candida albicans. BMC Genomics 14: 842.
  • Buerth, C., Kovacic, F., Stock, J., Terfrüchte, M., Wilhelm, S., Jaeger, K.-E., Feldbruegge, M., Schipper, K., Ernst, J. F., Tielker, D. (2013) Uml2 is a novel CalB-type lipase of Ustilago maydis with phospholipase A activity.  Appl. Microbiol. Biotechnol.98: 4963-4973.
  • Swidergall, M., Ernst, A. M., Ernst, J. F. (2013) Candida albicans mucin Msb2 is a broad-range protectant against antimicrobial peptides. Antimicrob Agents Chemother 57: 3917-3922.
  • Schmidt, S.  K., Ebel, S., Keil,. E, Woite, C., Ernst, J. F., Benzin, A. E., Rupp, J., Däubener, W. (2013) Regulation of IDO activity by oxygen supply: inhibitory effects on antimicrobial and immunoregulatory functions. PLoS One 8:e63301.
  • Kunigo, M., Buerth, C., Tielker, D., and Ernst, J. F. (2013) Heterologous protein secretion by Candida utilis. Appl Microbiol Biotechnol 97: 7357–7368.
  • Szafranski-Schneider, E., Swidergall, M., Cottier, F., Tielker, D., Román, E., Pla, J., and  Ernst, J. F. (2012) Msb2 shedding protects Candida albicans against antimicrobial peptides. PLoS Pathogens 8: e1002501
  • Lassak, T., Schneider, E.,, Bussmann, M., Kurtz, D., Manak, J. R., Srikantha, T., Soll, D. R., and Ernst, J. F. (2011) Target specificity of the Candida albicans Efg1 regulator. Mol Microbiol 82: 602-618. (Selected article by "Faculty of 1000") Pubmed
  • Buerth, C., Heilmann, C.J., Klis, F.M., de Koster, C.G., Ernst, J.F., and Tielker, D. (2011) Growth-dependent secretome of Candida utilis. Microbiology 157: 2493-2503. Pubmed
  • Ernst, J. F., and Pla, J. (2011) Signaling the glycoshield: maintenance of the Candida albicans cell wall. Int J Med Microbiol. 301: 378-383. Pubmed
  • Stichternoth, C., Fraund, A., Setiadi, S., Giasson, L., Vecchiarelli, A., and Ernst, J. F. (2011) Sch9 kinase integrates hypoxia and CO2 sensing to suppress hyphal morphogenesis in Candida albicans. Eukaryot Cell 10:502-511. Pubmed
  • Cantero, P. D., and Ernst, J. F. (2011) Damage to the glycoshield activates PMT-directed O-mannosylation via the Msb2-Cek1 pathway in Candida albicans. Mol Microbiol 80:715-725. Pubmed
  • Moreno, I., Martinez-Esparza, M., Laforet, L. C., Sentandreu, R., Ernst, J. F., and Valentin, E. (2010) Dosage-dependent roles of the Cwt1 transcription factor for cell wall architecture, morphogenesis, drug sensitivity and virulence in Candida albicans. Yeast 27: 77-87. Pubmed
  • Román, E., Cottier, F., Ernst, J. F., and Pla, J. (2009) The signaling mucin Msb2 controls the activation of the Cek1 MAP kinase in Candida albicans. Eukaryot Cell 8: 1235-1249. Pubmed
  • Willger, S. D., Ernst, J. F., Alspaugh, J. A., and Lengeler, K. B. (2009) Characterization of the PMT gene family in Cryptococcus neoformans. PLoS ONE 4: e6321. Pubmed
  • Tielker, D., Eichhof, I., Jaeger, K.-E., and Ernst, J. F. (2009) FMN-based fluorescent protein as an oxygen-independent reporter in Candida albicans and Saccharomyces cerevisiae. Eukaryot Cell 8: 913-915. Pubmed
  • Stichternoth, C., and Ernst, J. F. (2009) Hypoxic adaptation by Efg1 regulates biofilm formation of Candida albicans. Appl Environ Microbiol 75: 3663-3672. Pubmed
  • Ernst, J. F., and Tielker, D. (2009) Responses to hypoxia in fungal pathogens. Cell Microbiol 11: 183-190. Pubmed
  • Fradin, C., Slomianny, M.C., Mille, C., Masset, A., Sundstrom, P., Ernst, J. F., Michalski, J.C., and Poulain, D. (2008) ß-1,2 oligomannose adhesion epitopes are widely distributed over the four families of Candida albicans cell wall mannoproteins and associated through both N- and O-glycosylation processes. Infect Immun 76: 4509-4517. Pubmed
  • Noffz, C., Liedschulte, V. Lengeler, K., and Ernst, J. F. (2008) Functional mapping of the Candida albicans Efg1 regulator. Eukaryot Cell 7: 881-893. (Selected article by "Faculty of 1000") Pubmed
  • Lengeler, K., Tielker, D. and Ernst, J. F. (2008) Protein-O-mannosyltransferases in virulence and development. Cell Mol Life Sci 65, 528-544. Pubmed
  • Corbucci, C., Cenci, E., Skrzypek, F., Gabrielli, E., Mosci, P., Ernst, J. F., Bistoni, F., and Vecchiarelli, A. (2007) Immune response to Candida albicans is preserved despite defect in O-glycosylation of secretory proteins. Med Mycol 45: 709–719. Pubmed
  • Wittschier, N., Lengsfeld, C., Vorthems, S., Stratmann, U., Ernst, J. F., Verspohl, E. J., and Hensel, A. (2007) Large molecules as anti-adhesive compounds against pathogens. J Pharm Pharmacol 50: 3488-3492. Pubmed
  • Cantero, P. D., Lengsfeld, C., Prill, S. K.-H., Subanović, M., Román, E., Pla, J. and Ernst, J. F. (2007) Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans. Mol Microbiol 64: 1115-1128. Pubmed
  • Peltroche-Llacsahuanga, H., Goyard, S., D´Enfert, C., Prill, S. K.-H., and Ernst, J. F. (2006) Protein-O-mannosyltransferase-isoforms regulate biofilm formation of Candida albicans. Antimicrob Agents Chemother 50: 3488-3492. Pubmed
  • Setiadi, E. R., Doedt, T., Cottier, F., Noffz, C., and Ernst, J. F. (2006) Transcriptional response of Candida albicans to hypoxia: linkage of oxygen-sensing- and Efg1p-regulatory networks. J Mol Biol 361: 399-411. (Selected article by "Faculty of 1000") Pubmed
  • Pasrija, R., Krishnamurthy, S., Prasad, T., Ernst, J. F., and Prasad, R. (2005) Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans. J Antimicrob Chemother 55: 905-913. Pubmed
  • Rouabhia, M., Schaller, M., Vecchiarelli, A., Prill, S. K.-H., Giasson, L., and Ernst, J. F. (2005) Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases (Pmt proteins). Infect Immun 73: 4571-4580. Pubmed
  • D'Enfert, C., Goyard, S., Rodriguez-Arnaveilhe, S., Frangeul, L., Jones, L., Tekaia, F., Bader, O., Albrecht, A., Castillo, L., Dominguez, A., Ernst, J. F., Fradin, C., Gaillardin, C., Garcia-Sanchez, S., de Groot, P., Hube, B., Klis, F. M., Krishnamurthy, S., Kunze, D., Lopez, M. C., Mavor, A., Martin, N., Moszer, I., Onesime, D., Perez-Martin, J., Sentandreu, R., Valentin, E., and Brown, A. J. (2005) CandidaDB: a genomic database for Candida albicans pathogenomics. Nucl Acids Res 33: D353-D357. Pubmed
  • Prill, S. K.-H., Klinkert, B., Timpel, C., Gale, C. A., Schröppel, K., and Ernst, J. F. (2005) PMT family of Candida albicans: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance. Mol Microbiol 55: 546-560. Pubmed
  • Weber, Y., Prill, S. K.-H., and Ernst, J.F. (2004) Pmt-mediated O-glycosylation stabilizes an essential element of the secretory apparatus (Sec20p) in Candida albicans. Eukaryot Cell 3: 1164-1168. Pubmed
  • Doedt, T., Krishnamurthy, S., Bockmühl, D. P., Tebarth, B., Stempel, C., Russell, C. L., Brown, A. J. P., and Ernst, J. F. (2004) APSES proteins regulate morphogenesis and metabolism in Candida albicans. Mol Biol Cell 15: 3167-3180. Pubmed
  • Krishnamurthy, S., Plaîne, A., Albert, J., Prasad, T., Prasad, R., and Ernst, J. F. (2004) Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans. Microbiology 150: 1991-2003. Pubmed
  • Tebarth, B., Doedt, T., Krishnamurthy, S., Weide, M., Monterola, F., Dominguez, A., and Ernst, J. F. (2003) Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of  the EFG1 gene. J Mol Biol 329: 949 - 962. Pubmed
  • Haas, H., Schoeser, M., Lesuisse, E., Ernst, J.F., Parson, W., Abt, B., Winkelmann, G., and Oberegger, H. (2003) Characterisation of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C. Biochem J 371: 505-513. Pubmed
  • Weber, Y. and Ernst, J.F. (2002) Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicans. Mol Genet Genom 47: 89-102. Pubmed
  • Heymann, P., Gerads, M., Schaller, M., Dromer, F., Winkelmann, G., and Ernst, J. F. (2002) The Sit1/Arn1 transporter of Candida albicans mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect Immun 70: 5246-5266. Pubmed
  • Gruber, A., Lell, C. P., Speth, C., Stoiber, H., Lass-Florl, C., Sonneborn, A., Ernst, J. F., Dierich, M. P., and Würzner,  R. (2001) Human immunodeficiency virus type 1 Tat binds to Candida albicans, inducing hyphae but augmenting phagocytosis in vitro. Immunology 104: 455-461. Pubmed
  • Bockmühl, D. P., Krishnamurthy, S., Gerads, M., Sonneborn, A., and Ernst, J. F. (2001) Distinct and redundant roles of the two protein kinase A isoforms Tpk1p and Tpk2p in morphogenesis and growth of Candida albicans. Mol Microbiol 42: 1243-1257. Pubmed
  • Ernst, J. F., and Prill, S. K.-H. (2001) O-glycosylation. Med Mycol 39: Suppl. I, 67-74. Pubmed
  • Ernst, J. F., and Bockmühl, D. P. (2001) Gene expression and genetic techniques. In: Candida and Candidiasis, Editor R. Calderone, ASM Press Washington, 267-278.  
  • Bockmühl, D. P., and Ernst, J. F. (2001) A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans. Genetics 157: 1555-1567. Pubmed
  • Weber, Y., Santore, U. J., Ernst, J. F., and Swoboda, R. K. (2001) Divergence of eukaryotic secretory components: the Candida albicans homolog to the Saccharomyces cerevisiae Sec20 protein is N-terminally truncated and its levels determine antifungal resistance and growth. J Bacteriol 183: 46-54. Pubmed
  • Ernst, J. F. (2000) Transcription factors in Candida albicans: Environmental control of morphogenesis. Microbiology 146: 1829-1839. Pubmed        
  • Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Biometals 13: 65-72. Pubmed 
  • Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) Identification and substrate specificity of a ferrichrome-type siderophore transporter (Arn1p) in Saccharomyces cerevisiae. FEMS Microbiol Lett 186: 221-227. Pubmed
  • Timpel, C., Zink, S., Strahl-Bolsinger, S., Schröppel, K., and Ernst, J. (2000) Morphogenesis, adhesive properties and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen Candida albicans. J Bacteriol 182: 3063-3071. Pubmed
  • Ernst, J. F. (2000) Regulation of dimorphism in Candida albicans. In: Dimorphism in human pathogenic and apathogenic yeasts (edts. J. F. Ernst and A. Schmidt), Contributions to Microbiology 5: 98-111. Pubmed
  • Sonneborn, A., Bockmühl, D. P., Gerads; M., Kurpanek, K., Sanglard, D., and Ernst, J. F. (2000) Protein kinase A encoded by TPK2 regulates dimorphism of the human pathogen Candida albicans. Mol Microbiol 35: 386-396. Pubmed
  • Weide, M., Tebarth, B., and Ernst, J. F. (1999) Caco-2 monolayer as a model for transepithelial migration of the fungal pathogen Candida albicans. Mycoses 42: Suppl. 2, 61-67. Pubmed
  • Heymann, P., Ernst, J.F. and Winkelmann, G. (1999) Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily. Biometals 12: 301-306. Pubmed
  • Sonneborn, A., Bockmühl, D. P., and Ernst, J. F. (1999) Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator. Infect Immun 67: 5514-5517. Pubmed
  • Sonneborn, A., Tebarth, B., and Ernst, J. F. (1999) Control of white-opaque phenotypic switching in Candida albicans by the Efg1p morphogenetic regulator. Infect Immun 67: 4655-4660. Pubmed
  • Lorberg, A., Kirchrath, L., Ernst, J. F., and Heinisch, J. J. (1999) Genetic and biochemical characterization of phosphofructokinase from the opportunistic pathogenic yeast Candida albicans. Eur J Biochem 259: 1-11. Pubmed
  • Gerads, M., and Ernst, J.F. (1998) Overlapping coding regions of two essential chromosomal genes (CCT8, TRP1) in the fungal pathogen Candida albicans. Nucl Acids Res 26: 5061-5066. Pubmed
  • Rademacher, F., Kehren, Stoldt, V. R., and Ernst, J. F. (1998) Chaperonins as specific dominant-negative suppressors of fungal morphogenesis and RAS signal transduction pathways. Microbiology 114: 2951-2960. Pubmed
  • Timpel, C., Strahl-Bolsinger, S., Ziegelbauer, K., and Ernst, J. F. (1998) Protein O-mannosylation by Pmt1p determines morphogenesis, adherence, susceptibility to antifungals and virulence of the fungal pathogen Candida albicansJ Biol Chem 273: 20837-20846. Pubmed  
  • Wickert, S., Finck, M., Herz, B., and Ernst, J. F. (1998) A small protein (Ags1p) and the Pho80p-Pho85p kinase complex contribute to aminoglycoside antibiotic resistance of the yeast Saccharomyces cerevisiae. J Bacteriol 180:1887-1894. Pubmed
  • Delbrück, S., Sonneborn, A., Gerads, M., Grablowitz, A., and Ernst, J.F. (1997) Characterization and coordinate regulation of genes encoding ribosomal protein genes L39, S7 and L29 of the human pathogen Candida albicans. Yeast 13: 1199-1210.  Pubmed
  • Leuker, C. ., Sonneborn, A., Delbrück, S., and Ernst, J. F. (1997) Sequence and regulation of the PCK1 gene encoding phosphoenolpyruvate carboxykinase of the fungal pathogen Candida albicans. Gene 192: 235-240.  Pubmed
  • Stoldt, V. R., Sonneborn, A., Leuker, C., and Ernst, J. F. (1997) Efg1, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J 16:1982-1991. Pubmed
  • Publications before 1997
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