Rastogi, S.K., van Wijlick, L., Ror, S., Lee, K.K., Román, E., Agarwal, P., Manzoor, N., Gow, N.A.R., Pla, J., Ernst, J.F., Panwar, S.L. (2019) Ifu5, a WW domain-containing protein interacts with Efg1 to achieve coordination of normoxic and hypoxic functions to influence pathogenicity traits in Candida albicans. Cell. Microbiol. Nov 17:e13140.
Desai, P.R., Lengeler, K., Kapitan, M., Janßen, S.M., Alepuz, P., Jacobsen, I.D., Ernst, J.F. (2018) The 5' untranslated region of the EFG1 transcript promotes its translation to regulate hyphal morphogenesis in Candida albicans. mSphere 3: e00280-18. (Selected article by "Faculty of 1000")
Pohlers, S., Martin, R., Krüger, T., Hellwig, D., Hänel, F., Kniemeyer, O., Saluz, H.P., Van Dijck, P., Ernst, J.F., Brakhage, A., Mühlschlegel, F.A., Kurzai, O. (2017) Lipid signaling via Pkh1/2 regulates fungal CO2 sensing through the kinase Sch9. MBio 8: pii: e02211-16.
van Wijlick, L., Geissen, R., Hilbig, J.S., Lagadec, Q., Cantero, P.D., Pfeifer, E., Juchimiuk, M., Kluge, S., Wickert, S., Alepuz, P., Ernst, J.F. (2016) Dom34 links translation to protein O-mannosylation.PLoS Genet. 12: e1006395. DMYKG publication award
van Wijlick, L., Swidergall, M., Brandt, P., Ernst, J.F. (2016) Candida albicans responds to glycostructure damage by Ace2-mediated feedback regulation of Cek1 signaling. Mol. Microbiol. 102: 827-849.
Buerth, C., Tielker, D., Ernst, J.F. (2016) Candida utilis and Cyberlindnera (Pichia) jadinii: yeast relatives with expanding applications. Appl. Microbiol. Biotechnol. 100: 6981-6990.
Kapitan, M., Eichhof, I., Lagadec, Q., Ernst, J.F. (2016) Click beetle luciferases as dual reporters of gene expression in Candida albicans. Microbiology, 162: 1310-1320.
Eichhof, I., Ernst, J.F. (2016) Oxygen-independent FbFP: Fluorescent sentinel and oxygen sensor component in Saccharomyces cerevisiae and Candida albicans. Fungal Genet. Biol.92: 14-25. Corrigendum 93: 62.
Desai, P., van Wijlick, L., Kurtz, D., Juchimiuk, M., Ernst, J.F. (2015) Hypoxia and temperature regulated morphogenesis in Candida albicans. PLoS Genet. 11: e1005447.
Rupp, O., Brinkrolf. K., Buerth, C., Kunigo, M., Schneider, J., Jaenicke, S., Goesmann, A., Pühler, A., Jaeger, K.E., Ernst, J.F. (2015) The structure of the Cyberlindnera jadinii genome and its relation to Candida utilis analyzed by the occurrence of single nucleotide polymorphisms. J. Biotechnol.211: 20-30.
Kunigo, M., Buerth, C., Ernst, J.F. (2015) Secreted xylanase XynA mediates utilization of xylan as sole carbon source in Candida utilis. Appl. Microbiol. Biotechnol. 99: 8055-8064.
Swidergall, M., van Wijlick, L., Ernst, J.F. (2015) Signaling domains of mucin Msb2 in Candida albicans. Eukaryot. Cell14: 359-370.
Varshney, N., Schaekel, A., Singha, R., Chakraborty, T., van Wijlick, L., Ernst, J. F., Sanyal, K. (2015) A surprising role for the Sch9 protein kinase in chromosome segregation in Candida albicans. Genetics199: 671-674. (Comment in SGD News & Newsworthy)
Swidergall, M., Ernst, J. F. (2014) Interplay between Candida albicans and the antimicrobial peptide armory. Eukaryot. Cell 13: 950-957.
Juchimiuk, M., Orłowski, J., Gawarecka, K., Swieżewska, E., Ernst, J. F., Palamarczyk, G. (2014) Candida albicans cis-prenyltransferase Rer2 is required for protein glycosylation, cell wall integrity and hypha formation.Fungal Genet. Biol.69C:1-12.
Schaekel, A., Desai, P. R., Ernst, J. F. (2013) Morphogenesis-regulated localization of protein kinase A to genomic sites in Candida albicans. BMC Genomics14: 842.
Buerth, C., Kovacic, F., Stock, J., Terfrüchte, M., Wilhelm, S., Jaeger, K.-E., Feldbruegge, M., Schipper, K., Ernst, J. F., Tielker, D. (2013) Uml2 is a novel CalB-type lipase of Ustilago maydis with phospholipase A activity. Appl. Microbiol. Biotechnol.98: 4963-4973.
Swidergall, M., Ernst, A. M., Ernst, J. F. (2013) Candida albicans mucin Msb2 is a broad-range protectant against antimicrobial peptides. Antimicrob Agents Chemother57: 3917-3922.
Schmidt, S. K., Ebel, S., Keil,. E, Woite, C., Ernst, J. F., Benzin, A. E., Rupp, J., Däubener, W. (2013) Regulation of IDO activity by oxygen supply: inhibitory effects on antimicrobial and immunoregulatory functions. PLoS One8:e63301.
Szafranski-Schneider, E., Swidergall, M., Cottier, F., Tielker, D., Román, E., Pla, J., and Ernst, J. F. (2012) Msb2 shedding protects Candida albicans against antimicrobial peptides. PLoS Pathogens8: e1002501
Lassak, T., Schneider, E.,, Bussmann, M., Kurtz, D., Manak, J. R., Srikantha, T., Soll, D. R., and Ernst, J. F. (2011) Target specificity of the Candida albicans Efg1 regulator. Mol Microbiol82: 602-618. (Selected article by "Faculty of 1000") Pubmed
Buerth, C., Heilmann, C.J., Klis, F.M., de Koster, C.G., Ernst, J.F., and Tielker, D. (2011) Growth-dependent secretome of Candida utilis. Microbiology157: 2493-2503. Pubmed
Ernst, J. F., and Pla, J. (2011) Signaling the glycoshield: maintenance of the Candida albicans cell wall. Int J Med Microbiol.301: 378-383. Pubmed
Stichternoth, C., Fraund, A., Setiadi, S., Giasson, L., Vecchiarelli, A., and Ernst, J. F. (2011) Sch9 kinase integrates hypoxia and CO2 sensing to suppress hyphal morphogenesis in Candida albicans. Eukaryot Cell 10:502-511. Pubmed
Cantero, P. D., and Ernst, J. F. (2011) Damage to the glycoshield activates PMT-directed O-mannosylation via the Msb2-Cek1 pathway in Candida albicans. Mol Microbiol80:715-725. Pubmed
Moreno, I., Martinez-Esparza, M., Laforet, L. C., Sentandreu, R., Ernst, J. F., and Valentin, E. (2010) Dosage-dependent roles of the Cwt1 transcription factor for cell wall architecture, morphogenesis, drug sensitivity and virulence in Candida albicans. Yeast27: 77-87. Pubmed
Román, E., Cottier, F., Ernst, J. F., and Pla, J. (2009) The signaling mucin Msb2 controls the activation of the Cek1 MAP kinase in Candida albicans. Eukaryot Cell8: 1235-1249. Pubmed
Willger, S. D., Ernst, J. F., Alspaugh, J. A., and Lengeler, K. B. (2009) Characterization of the PMT gene family in Cryptococcus neoformans. PLoS ONE4: e6321. Pubmed
Tielker, D., Eichhof, I., Jaeger, K.-E., and Ernst, J. F. (2009) FMN-based fluorescent protein as an oxygen-independent reporter in Candida albicans and Saccharomyces cerevisiae. Eukaryot Cell8: 913-915. Pubmed
Stichternoth, C., and Ernst, J. F. (2009) Hypoxic adaptation by Efg1 regulates biofilm formation of Candida albicans. Appl Environ Microbiol75: 3663-3672. Pubmed
Ernst, J. F., and Tielker, D. (2009) Responses to hypoxia in fungal pathogens. Cell Microbiol11: 183-190. Pubmed
Fradin, C., Slomianny, M.C., Mille, C., Masset, A., Sundstrom, P., Ernst, J. F., Michalski, J.C., and Poulain, D. (2008) ß-1,2 oligomannose adhesion epitopes are widely distributed over the four families of Candida albicans cell wall mannoproteins and associated through both N- and O-glycosylation processes. Infect Immun 76: 4509-4517. Pubmed
Noffz, C., Liedschulte, V. Lengeler, K., and Ernst, J. F. (2008) Functional mapping of the Candida albicans Efg1 regulator. Eukaryot Cell7: 881-893. (Selected article by "Faculty of 1000") Pubmed
Lengeler, K., Tielker, D. and Ernst, J. F. (2008) Protein-O-mannosyltransferases in virulence and development. Cell Mol Life Sci 65, 528-544. Pubmed
Corbucci, C., Cenci, E., Skrzypek, F., Gabrielli, E., Mosci, P., Ernst, J. F., Bistoni, F., and Vecchiarelli, A. (2007) Immune response to Candida albicans is preserved despite defect in O-glycosylation of secretory proteins. Med Mycol45: 709–719. Pubmed
Wittschier, N., Lengsfeld, C., Vorthems, S., Stratmann, U., Ernst, J. F., Verspohl, E. J., and Hensel, A. (2007) Large molecules as anti-adhesive compounds against pathogens. J Pharm Pharmacol50: 3488-3492. Pubmed
Cantero, P. D., Lengsfeld, C., Prill, S. K.-H., Subanović, M., Román, E., Pla, J. and Ernst, J. F. (2007) Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans. Mol Microbiol64: 1115-1128. Pubmed
Peltroche-Llacsahuanga, H., Goyard, S., D´Enfert, C., Prill, S. K.-H., and Ernst, J. F. (2006) Protein-O-mannosyltransferase-isoforms regulate biofilm formation of Candida albicans. Antimicrob Agents Chemother50: 3488-3492. Pubmed
Setiadi, E. R., Doedt, T., Cottier, F., Noffz, C., and Ernst, J. F. (2006) Transcriptional response of Candida albicans to hypoxia: linkage of oxygen-sensing- and Efg1p-regulatory networks. J Mol Biol361: 399-411. (Selected article by "Faculty of 1000") Pubmed
Pasrija, R., Krishnamurthy, S., Prasad, T., Ernst, J. F., and Prasad, R. (2005) Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans. J Antimicrob Chemother55: 905-913. Pubmed
Rouabhia, M., Schaller, M., Vecchiarelli, A., Prill, S. K.-H., Giasson, L., and Ernst, J. F. (2005) Virulence of the fungal pathogen Candida albicans requires the five isoforms of protein mannosyltransferases (Pmt proteins). Infect Immun73: 4571-4580. Pubmed
D'Enfert, C., Goyard, S., Rodriguez-Arnaveilhe, S., Frangeul, L., Jones, L., Tekaia, F., Bader, O., Albrecht, A., Castillo, L., Dominguez, A., Ernst, J. F., Fradin, C., Gaillardin, C., Garcia-Sanchez, S., de Groot, P., Hube, B., Klis, F. M., Krishnamurthy, S., Kunze, D., Lopez, M. C., Mavor, A., Martin, N., Moszer, I., Onesime, D., Perez-Martin, J., Sentandreu, R., Valentin, E., and Brown, A. J. (2005) CandidaDB: a genomic database for Candida albicans pathogenomics. Nucl Acids Res 33: D353-D357. Pubmed
Prill, S. K.-H., Klinkert, B., Timpel, C., Gale, C. A., Schröppel, K., and Ernst, J. F. (2005) PMT family of Candida albicans: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance. Mol Microbiol55: 546-560. Pubmed
Weber, Y., Prill, S. K.-H., and Ernst, J.F. (2004) Pmt-mediated O-glycosylation stabilizes an essential element of the secretory apparatus (Sec20p) in Candida albicans. Eukaryot Cell3: 1164-1168. Pubmed
Doedt, T., Krishnamurthy, S., Bockmühl, D. P., Tebarth, B., Stempel, C., Russell, C. L., Brown, A. J. P., and Ernst, J. F. (2004) APSES proteins regulate morphogenesis and metabolism in Candida albicans. Mol Biol Cell15: 3167-3180. Pubmed
Krishnamurthy, S., Plaîne, A., Albert, J., Prasad, T., Prasad, R., and Ernst, J. F. (2004) Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans. Microbiology150: 1991-2003. Pubmed
Tebarth, B., Doedt, T., Krishnamurthy, S., Weide, M., Monterola, F., Dominguez, A., and Ernst, J. F. (2003) Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of the EFG1 gene. J Mol Biol 329: 949 - 962. Pubmed
Haas, H., Schoeser, M., Lesuisse, E., Ernst, J.F., Parson, W., Abt, B., Winkelmann, G., and Oberegger, H. (2003) Characterisation of the Aspergillus nidulans transporters for the siderophores enterobactin and triacetylfusarinine C. Biochem J371: 505-513. Pubmed
Weber, Y. and Ernst, J.F. (2002) Sec20p-interacting proteins (Tip20p, Ufe1p) in the retrograde secretory pathway of the fungal pathogen Candida albicans. Mol Genet Genom47: 89-102. Pubmed
Heymann, P., Gerads, M., Schaller, M., Dromer, F., Winkelmann, G., and Ernst, J. F. (2002) The Sit1/Arn1 transporter of Candida albicans mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion. Infect Immun70: 5246-5266. Pubmed
Gruber, A., Lell, C. P., Speth, C., Stoiber, H., Lass-Florl, C., Sonneborn, A., Ernst, J. F., Dierich, M. P., and Würzner, R. (2001) Human immunodeficiency virus type 1 Tat binds to Candida albicans, inducing hyphae but augmenting phagocytosis in vitro. Immunology104: 455-461. Pubmed
Bockmühl, D. P., Krishnamurthy, S., Gerads, M., Sonneborn, A., and Ernst, J. F. (2001) Distinct and redundant roles of the two protein kinase A isoforms Tpk1p and Tpk2p in morphogenesis and growth of Candida albicans. Mol Microbiol42: 1243-1257. Pubmed
Ernst, J. F., and Prill, S. K.-H. (2001) O-glycosylation. Med Mycol39: Suppl. I, 67-74. Pubmed
Ernst, J. F., and Bockmühl, D. P. (2001) Gene expression and genetic techniques. In: Candida and Candidiasis, Editor R. Calderone, ASM Press Washington, 267-278.
Bockmühl, D. P., and Ernst, J. F. (2001) A potential phosphorylation site for an A-type kinase in the Efg1 regulator protein contributes to hyphal morphogenesis of Candida albicans. Genetics157: 1555-1567. Pubmed
Weber, Y., Santore, U. J., Ernst, J. F., and Swoboda, R. K. (2001) Divergence of eukaryotic secretory components: the Candida albicans homolog to the Saccharomyces cerevisiae Sec20 protein is N-terminally truncated and its levels determine antifungal resistance and growth. J Bacteriol183: 46-54. Pubmed
Ernst, J. F. (2000) Transcription factors in Candida albicans: Environmental control of morphogenesis. Microbiology 146: 1829-1839. Pubmed
Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) A gene of the major facilitator superfamily encodes a transporter for enterobactin (Enb1p) in Saccharomyces cerevisiae. Biometals13: 65-72. Pubmed
Heymann, P., Ernst, J. F., and Winkelmann, G. (2000) Identification and substrate specificity of a ferrichrome-type siderophore transporter (Arn1p) in Saccharomyces cerevisiae. FEMS Microbiol Lett186: 221-227. Pubmed
Timpel, C., Zink, S., Strahl-Bolsinger, S., Schröppel, K., and Ernst, J. (2000) Morphogenesis, adhesive properties and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen Candida albicans. J Bacteriol 182: 3063-3071. Pubmed
Ernst, J. F. (2000) Regulation of dimorphism in Candida albicans. In: Dimorphism in human pathogenic and apathogenic yeasts (edts. J. F. Ernst and A. Schmidt), Contributions to Microbiology5: 98-111. Pubmed
Sonneborn, A., Bockmühl, D. P., Gerads; M., Kurpanek, K., Sanglard, D., and Ernst, J. F. (2000) Protein kinase A encoded by TPK2 regulates dimorphism of the human pathogen Candida albicans. Mol Microbiol35: 386-396. Pubmed
Weide, M., Tebarth, B., and Ernst, J. F. (1999) Caco-2 monolayer as a model for transepithelial migration of the fungal pathogen Candida albicans. Mycoses 42: Suppl. 2, 61-67. Pubmed
Heymann, P., Ernst, J.F. and Winkelmann, G. (1999) Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily. Biometals12: 301-306. Pubmed
Sonneborn, A., Bockmühl, D. P., and Ernst, J. F. (1999) Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator. Infect Immun67: 5514-5517. Pubmed
Sonneborn, A., Tebarth, B., and Ernst, J. F. (1999) Control of white-opaque phenotypic switching in Candida albicans by the Efg1p morphogenetic regulator. Infect Immun67: 4655-4660. Pubmed
Lorberg, A., Kirchrath, L., Ernst, J. F., and Heinisch, J. J. (1999) Genetic and biochemical characterization of phosphofructokinase from the opportunistic pathogenic yeast Candida albicans. Eur J Biochem259: 1-11. Pubmed
Gerads, M., and Ernst, J.F. (1998) Overlapping coding regions of two essential chromosomal genes (CCT8, TRP1) in the fungal pathogen Candida albicans. Nucl Acids Res26: 5061-5066. Pubmed
Rademacher, F., Kehren, Stoldt, V. R., and Ernst, J. F. (1998) Chaperonins as specific dominant-negative suppressors of fungal morphogenesis and RAS signal transduction pathways. Microbiology114: 2951-2960. Pubmed
Timpel, C., Strahl-Bolsinger, S., Ziegelbauer, K., and Ernst, J. F. (1998) Protein O-mannosylation by Pmt1p determines morphogenesis, adherence, susceptibility to antifungals and virulence of the fungal pathogen Candida albicans. J Biol Chem273: 20837-20846. Pubmed
Wickert, S., Finck, M., Herz, B., and Ernst, J. F. (1998) A small protein (Ags1p) and the Pho80p-Pho85p kinase complex contribute to aminoglycoside antibiotic resistance of the yeast Saccharomyces cerevisiae. J Bacteriol180:1887-1894. Pubmed
Delbrück, S., Sonneborn, A., Gerads, M., Grablowitz, A., and Ernst, J.F. (1997) Characterization and coordinate regulation of genes encoding ribosomal protein genes L39, S7 and L29 of the human pathogen Candida albicans. Yeast13: 1199-1210. Pubmed
Leuker, C. ., Sonneborn, A., Delbrück, S., and Ernst, J. F. (1997) Sequence and regulation of the PCK1 gene encoding phosphoenolpyruvate carboxykinase of the fungal pathogen Candida albicans. Gene192: 235-240. Pubmed
Stoldt, V. R., Sonneborn, A., Leuker, C., and Ernst, J. F. (1997) Efg1, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J16:1982-1991. Pubmed
